Fecal Transplant and Bifidobacterium Treatments Modulate Gut Clostridium

Gastrointestinal dysfunction and gut microbiota dysbiosis, including an overall increase in Clostridium have been reported in cases of Autism. Modulation of the gut microbiota as a promising venue of intervention to ameliorate autistic symptoms. This study explored the use of two different interventions that target the microbiota in a rodent model of autism. It assessed social behavior, the levels of different fecal Clostridium spp., and hippocampal transcript levels as outcomes of these interve